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Autocamtide 2

CAS No. 129198-88-5

Autocamtide 2 ( Autocamtide II )

产品货号. M29916 CAS No. 129198-88-5

Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2556 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货

生物学信息

  • 产品名称
    Autocamtide 2
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family.
  • 产品描述
    Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family.(In Vitro):The Ca/calmodulin dependent protein kinases (CaMKs) are multifunctional serine/threonine kinases whose activity are regulated through Ca2+ signaling. It is multifunctional best known for its critical role in learning and memory. Recent studies demonstrates that high levels of different isoform of CaMK, especially for CaMKII, expresses in several cancers such as lung, breast, prostate and colon cancer. CaMKII phosphorylates nearly 40 different proteins, including enzymes, ion channels, kinases, and transcription factors and plays a critical role in the regulation of proliferation, differentiation and survival of various cancer cells.
  • 体外实验
    The Ca/calmodulin dependent protein kinases (CaMKs) are multifunctional serine/threonine kinases whose activity are regulated through Ca2+ signaling. It is multifunctional best known for its critical role in learning and memory. Recent studies demonstrates that high levels of different isoform of CaMK, especially for CaMKII, expresses in several cancers such as lung, breast, prostate and colon cancer. CaMKII phosphorylates nearly 40 different proteins, including enzymes, ion channels, kinases, and transcription factors and plays a critical role in the regulation of proliferation, differentiation and survival of various cancer cells.
  • 体内实验
    ——
  • 同义词
    Autocamtide II
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    129198-88-5
  • 分子量
    1527.77
  • 分子式
    C65H118N22O20
  • 纯度
    >98% (HPLC)
  • 溶解度
    H2O : 20 mg/mL (13.09 mM; Need ultrasonic)
  • SMILES
    ——
  • 化学全称
    Sequence:Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

Wang YY, et al. The emerging role of CaMKII in cancer. Oncotarget. 2015 May 20;6(14):11725-34.
产品手册
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